Marijuana high: Strains, smoking, vaping, and edibles

Edible highs tend to last longer than a smoking or vaping high. It can take between 30 and 90 minutes before you start to feel the effects of cannabis edibles. However, there are anecdotal reports of edibles producing a strong and sometimes debilitating high.

Effects of weed on the brain

In fact, slowly inhaling and focusing on comfort will get you further than trying to “milk” a hit by holding it in. Taking how long does it take for a dab pen to hit in bigger hits, but not holding the smoke longer. Still (it’s a popular belief that the longer you hold in marijuana smoke), the more potent the effects. THC is absorbed through the lungs in just a few seconds (so once you’ve taken a hit), keeping the smoke in doesn’t give you a stronger high.

Factors that affect a cannabis high

Given that THC and anandamide share similar properties, consuming cannabis can produce similar effects. Both of these cannabinoids demonstrate a strong affinity for binding to the endocannabinoid system’s receptors — CB1 and CB2. It turns out anandamide is responsible for much more than happiness.

THC is likely the primary cannabinoid you recognize from the cannabis plant. Hash (edibles), concentrates, vape carts, and other weed products can also be made by extracting these compounds from the plant. Cannabinoids and terpenes are released into your lungs and body when you heat and smoke bud. It’s a well-known fact that consuming cannabis buds results in a high.

The Risks of Holding in Hits For Too Long

When they consume cannabis, they experience a paradox effect, and in fact actually become anxious. As such (in these people anandamide doesn’t break down the same way), so they are naturally more relaxed. A naturally occurring enzyme called FAAH , fatty acid amide hydrolase, deactivates anandamide, and some individuals are genetically predisposed to producing less FAAH. In this case — it creates that sense of “bliss.” Notably, chocolate, yoga, and running also affect anandamide, so you can get a similar high — albeit less powerful — from these activities as well , think “runner’s high”,. Like a key in a lock (once a neurotransmitter binds to — or fits in — the correct receptor), it signals to your body to do something.

The negative effects of cannabis can be more pronounced in younger users. Cannabis has both short- and long-term effects in your body. CBD does interact with the endocannabinoid system. Method Onset PeakTotal durationSmoking and vaping Within minutes 20 to 30 minutes 2 to 3 hours Edibles 30 to 90 minutes 3 hours Within 24 hours A 2017 review identified the following times for the onset, peak, and total duration of a cannabis high. The duration of a cannabis high depends on a variety of different factors, including the dose and potency.

How marijuana works

A negative mindset, such as having a rough day, can lead to a disappointing smoking experience regardless of your fondness for weed. The entourage effect is a complex topic regarding cannabis, with much more to explore about how different cannabinoids and terpenes work together. While one puff might suffice for you, your friend could smoke an entire joint without flinching. It can help alleviate anxiety at one dose; however, at another dosage, it may worsen the condition. A small amount of weed may help relax you, but excessive consumption might increase feelings of anxiety.

With time, the body’s natural production of endocrines may significantly diminish, as cannabis chemicals replace the body’s own naturally occurring substances. The calming effect of cannabis arises from THC’s ability to slow communication between the brain and the rest of the body. Compared to edibles, smoking and vaping generally result in a quicker and more intense high.